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    Abdala: clarification on doubts about adverse events

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    Abdala: esclarecen dudas sobre eventos adversos

    The development of symptoms such as cough and fever, after the inoculation of the Abdala vaccine, is associated with the fact that the subjects received the immunogenic medication during the incubation period of the SARS-CoV-2 virus, in circumstances marked by the increase in infections during the community transmission phase.

    Due to repeated doubts from the population, Doctor in Medical Sciences Jacqueline Díaz Luis, II Degree specialist in Immunology, from the Roberto Rodríguez General Teaching Hospital, in the municipality of Morón, stated that these conditions are not registered in the technical file of the vaccine as adverse events. The doctor specified that the documentation is constantly updated at the State Center for the Control of Medicines and Medical Devices (CECMED by its Spanish initials), based on the collected evidence.

    Accumulated clinical experience shows that, in the case of Abdala, adverse events occur in a low amount and 97% are minor, with a tendency to disappear spontaneously, without the need for treatment.

    In the period between 24 and 48 hours after vaccination, mild events have been noted, most of them local ones --they are the most frequent, in 0.85% of patients--, referring to the presence of pain, stiffness and erythema in the inoculation site.

    Other temporary incidents are headache, sleepiness, asthenia and hypertension, evidenced in a range that oscillates between 0.1 and 0.5% of vaccinated subjects.

    Díaz Luis recalled that the protocol of the Ministry of Public Health contraindicates vaccination in people with indicative symptoms of COVID-19, infectious or decompensated chronic diseases, and permanent conditions such as anaphylaxis.

    However, if a person receives Abdala while presenting symptoms of SARS-CoV-2, nothing happens, but it is not recommended and it is temporarily contraindicated, considering that the vaccine will not have time to achieve the desired effect, therefore, it won't help in that state.

    In the case of infected patients, single-dose vaccines such as Soberana Plus (in the case of Cuba) are suggested to amplify the active natural immunity obtained after suffering from the disease.